Wisconsin Nathan Shock Center

Catalyzing research at the interface of aging, metabolism, and translation

The NIH/NIA sponsored WiNSC establishes a national hub for research quantifying, defining, and dissecting the causal role of metabolism in aging and age-related disease vulnerability. The effects of metabolic integrity extend beyond the fundamental biology of aging to the biology of age-related disease, and the most common age-associated diseases and conditions feature metabolic dysfunction. Operating across time-frames, from acute to chronic, and across scales, from cells to tissues to whole organisms, the biological mechanisms in metabolic regulation are highly conserved. WiNSC will facilitate translation of aging biology to human health, fuel innovation, and accelerate discovery.