Wisconsin Nathan Shock Center

About the Nathan Shock Centers

The National Institute on Aging (NIA), part of the National Institutes of Health (NIH), funds eight Nathan Shock Centers of Excellence in the Basic Biology of Aging. These centers honor Dr. Nathan Shock, a pioneer in gerontology, and provide advanced resources to accelerate research into the fundamental mechanisms of aging. Established in 1995, the program fosters collaboration and innovation across a national network of leading institutions.

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Wisconsin Nathan Shock Center

Catalyzing research at the interface of aging, metabolism, and translation

The NIH/NIA-sponsored Wisconsin Nathan Shock Center (WiNSC) serves as a national, highly interdisciplinary hub for research that quantifies, defines, and dissects the causal role of metabolism in aging and vulnerability to age-related disease. Metabolic integrity influences not only the biology of aging but also the biology of common age-associated conditions, where metabolic dysfunction is a hallmark. WiNSC fosters collaborations that span departments, methods, and institutions, reflecting the increasingly cross‑disciplinary nature of aging research.

Operating across time frames—from acute to chronic—and across scales—from cells to tissues to whole organisms—WiNSC investigates highly conserved mechanisms of metabolic regulation. By leveraging these insights, WiNSC aims to translate aging biology into strategies that improve human health, fuel innovation, and accelerate discovery.

A key part of WiNSC’s mission is supporting trainees and early‑career investigators through access to innovative methods, mentorship, and interdisciplinary research settings that help launch impactful careers in aging biology.

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